Kroncke Laboratory
Publications

Publications & preprints, 2010–2026

Full list from the lab’s CV. Kroncke Lab papers appear from 2019 onward; earlier work spans membrane-protein structural biology and spin-label NMR/EPR.

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2026

  • Tabet DR*, Cote AG*, Lancaster MC, Weile J, Rayhan A, Fotiadou I, Kishore N, Li R, Kuang D, Knapp JJ, Carrero CS, Taverniti O, Axakova A, Castelli JMP, Islam MM, Sowlati-Hashjin S, Gandhi A, Maaieh R, Garton M, Matreyek K, Fowler DM, Bourbon M, Pfisterer SG, Glazer AM, Kroncke BM, Parikh VN, Ashley EA, Knowles JW, Claussnitzer M, Cirulli ET, Hegele RA, Roden DM, MacRae CA, Roth FP. The functional landscape of coding variation in the familial hypercholesterolemia gene LDLR. Science. 2026 Feb 19;391(6787):eady7186. doi: 10.1126/science.ady7186. PubMed PMID: 41166440; PubMed Central PMCID: PMC12726852.PubMed ↗
  • Dauda K, Yamauchi K, Ku M, Mitchell DW, Shen A, Vanags L, Schmeckpeper J, Kannankeril PJ, Knollmann BC, O'Neill MJ, Kroncke BM*. Structural Evaluation of RYR2-CPVT Missense Variants and Continuous Bayesian Estimates of Their Penetrance. Circ Genom Precis Med. 2026 Apr;19(2):e005457. doi: 10.1161/CIRCGEN.125.005457. Epub 2026 Mar 27. PubMed PMID: 41889371; PubMed Central PMCID: PMC13108506. *corresponding authorPubMed ↗
  • In press · CirculationHarvey ML, Osborn E, Lancaster MC, Smith JE, Shen Q, Abe T, Cai R, Muhammad A, Kannankeril R, Yang T, Calandranis ME, Blackwell DJ, Dolder RE, Aldridge JL, Fleming MR, Blair MA, Soria E, O'Sullivan JW, Davogustto G, Kroncke BM, MacRae CA, Knollmann BC, Roth FP, Parikh VN, Ashley EA, Vandenberg JI, Ng CA, Roden DM, Glazer AM. Multimodal KCNQ1 Variant-Effect Maps Define Ion Channel Mechanisms and Disease Risk. Circulation, in press. Preprint: medRxiv 2025.12.15.25341924. doi: 10.64898/2025.12.15.25341924. Preprint PubMed PMID: 41445606; PMCID: PMC12724399.PubMed ↗
  • In press · Molecular & Cellular ProteomicsEgly CL, Barny L, Woo S, Mitchell D, Ku M, Knollmann BC, Plate L, Kroncke BM*. Kv11.1 (hERG) Protein Interaction Networks Connect Endocytic Trafficking to Polygenic Influences on Cardiac Repolarization. Mol Cell Proteomics, in press (accepted September 2026). Preprint: bioRxiv 2026.01.27.701872. doi: 10.64898/2026.01.27.701872. Preprint PubMed PMID: 41659607; PMCID: PMC12874042. *corresponding authorPubMed ↗
  • In review · EHJDevyn M. Mitchell, Matthew J. O’Neill, Loren Vanags, Nidhi Patel, Theresa Strickland, Giovanni Davogustto, M. Benjamin Shoemaker, Joe Elie Salem, Brett M. Kroncke*. Patient-derived Cellular Models of Polygenic Scores: Application to Long QT Syndrome. bioRxiv 2025.08.05.667271. doi: 10.1101/2025.08.05.667271. *corresponding authorDOI ↗
  • In review · CirculationBai FF, Chua K, Li D, Kirillova A, Yadav S, Staudt D, Yamamoto Y, De Jong HN, Müller LH, Fenzl K, Rungaramsin N, Huang Y, Reuter C, Zhang S, Krysov V, Njoroge J, Floyd BJ, Lakdawala NK, James CA, Cannie D, Elliott P, Mestroni L, Owens A, Merlo M, Krahn A, Mao C, Fatkin D, Vedantham V, Chahal A, Helms A, Wu JC, MacRae C, Gotthardt M, Roden D, Roth F, Ashley E, Meder B, Kroncke B, Tabet D, Cote A, Steinmetz LM, Glazer A, Mercola M, Parikh VN. Damaging RBM20 E-rich domain variants are not rescued by gene replacement. bioRxiv 2026.07.13.738343. doi: 10.64898/2026.07.13.738343. Preprint PubMed PMID: 42523282; PMCID: PMC13404807.PubMed ↗
  • ReviewGlazer AM, Tabet DR, Parikh VN, Kroncke BM, Cote AG, Yamamoto Y, Wang Q, Muhammad A, Lancaster MC, O'Neill MJ, Weile J, Yang T, Macrae CA, Ashley EA, Roth FP, Roden DM. Creating an atlas of variant effects to resolve variants of uncertain significance and guide cardiovascular medicine. Nat Rev Cardiol. 2026 Mar;23(3):149-163. doi: 10.1038/s41569-025-01201-7. Epub 2025 Sep 1. PubMed PMID: 40890511.PubMed ↗

2025

  • Mitchell D, Ullah R, Vanags L, Shen A, Jones L, Morris W, O'Neill MJ, Davogustto G, Shaffer C, Roden D, Shoemaker B, Williams H, Strickland T, Agee T, Johnson C, Kroncke B*. Generation of human induced pluripotent stem cell (hiPSC) lines from patients with extreme high and low polygenic scores for QT interval. Stem Cell Res. 2025 Apr;84:103691. doi: 10.1016/j.scr.2025.103691. Epub 2025 Feb 27. PubMed PMID: 40043554. *corresponding authorPubMed ↗
  • Patel N, Shen A, Wada Y, Blair M, Mitchell D, Vanags L, Woo S, Ku M, Dauda K, Morris W, Yang M, Knollmann BC, Salem JE, Glazer AM*, Kroncke BM*. A high-performance extracellular field potential analyzer for iPSC-derived cardiomyocytes. Sci Rep. 2025 Mar 15;15(1):8948. doi: 10.1038/s41598-025-88946-w. PubMed PMID: 40089568; PubMed Central PMCID: PMC11910505. *co-corresponding authorPubMed ↗
  • Ng CA, O'Neill MJ, Padigepati SR, Ting YL, Facio FM, Vatta M, Poll SR, Reuter JA, Vandenberg JI*, Kroncke BM*. Calibrated Functional Data Decrease Clinical Uncertainty for KCNH2-Related Long-QT Syndrome. Circ Genom Precis Med. 2025 Aug;18(4):e005204. doi: 10.1161/CIRCGEN.125.005204. Epub 2025 Jul 18. PubMed PMID: 40677236; PubMed Central PMCID: PMC12313180. *co-corresponding authorPubMed ↗
  • Gyawu RF, Beard TM, Tikunova S, Ulker A, Garcia SA, Knotts GM, Agee TA, Alam Afsar MN, Kroncke BM, Smith J, Davis J, Johnson CN. Molecular interactions of the NaV1.5 C-terminal domain: CaM sequestered the IQ motif from the CTD. J Biol Chem. 2025 Dec;301(12):110871. doi: 10.1016/j.jbc.2025.110871. Epub 2025 Oct 30. PubMed PMID: 41173394; PubMed Central PMCID: PMC12682251.PubMed ↗
  • Egly CL, Shen A, Do TQ, Tellet Cabiya C, Ritschel PA, Woo S, Ku M, Delisle BP, Kroncke BM*, Knollmann BC*. High-throughput screens identify genotype-specific therapeutics for channelopathies. JCI Insight. 2025 Sep 30;10(22):e191697. doi: 10.1172/jci.insight.191697. PubMed PMID: 41026531; PubMed Central PMCID: PMC12643509. *co-corresponding authorPubMed ↗

2024

  • Thomson KL, Jiang C, Richardson E, Westphal DS, Burkard T, Wolf CM, Vatta M, Harrison SM, Ingles J, Bezzina CR, Kroncke BM, Vandenberg JI, Ng CA. Clinical interpretation of KCNH2 variants using a robust PS3/BS3 functional patch clamp assay. HGG Adv. 2024 Apr;5(2):100270. doi: 10.1016/j.xhgg.2024.100270. Epub 2024 Jan 14. PubMed PMID: 38219013.PubMed ↗
  • O'Neill MJ, Ng CA, Aizawa T, Sala L, Bains S, Winbo A, Ullah R, Shen Q, Tan CY, Kozek K, Vanags LR, Mitchell DW, Shen A, Wada Y, Kashiwa A, Crotti L, Dagradi F, Musu G, Spazzolini C, Neves R, Bos JM, Giudicessi JR, Bledsoe X, Gamazon ER, Lancaster MC, Glazer AM, Knollmann BC, Roden DM, Weile J, Roth F, Salem JE, Earle N, Stiles R, Agee T, Johnson CN, Horie M, Skinner J, Ackerman MJ, Schwartz PJ, Ohno S, Vandenberg JI, Kroncke BM*. Multiplexed Assays of Variant Effect and Automated Patch Clamping Improve KCNH2-LQTS Variant Classification and Cardiac Event Risk Stratification. Circulation. 2024 Dec 3;150(23):1869-1881. doi: 10.1161/CIRCULATIONAHA.124.069828. Epub 2024 Sep 24. PubMed PMID: 39315434. *co-corresponding authorPubMed ↗

2023

  • O’Neill MJ, Sala L, Denjoy I, Wada Y, Kozek K, Crotti L, Dagradi F, Kotta MC, Spazzolini C, Leenhardt A, Salem JE, Kashiwa A, Ohno S, Tao R, Roden DM, Horie M, Extramiana F, Schwartz PJ, Kroncke BM*, Continuous Bayesian Variant Interpretation Accounts for Incomplete Penetrance among Mendelian Cardiac Channelopathies, Genetics in Medicine, March 2023, 25(3):100355. PMID: 36496179. *corresponding authorPubMed ↗
  • O'Neill MJ, Chen SN, Rumping L, Johnson R, van Slegtenhorst M, Glazer AM, Yang T, Solus JF, Laudeman J, Mitchell DW, Vanags LR, Kroncke BM, Anderson K, Gao S, Verdonschot JAJ, Brunner H, Hellebrekers D, Taylor MRG, Roden DM, Wessels MW, Lekanne Dit Deprez RH, Fatkin D, Mestroni L, Shoemaker MB. Multicenter clinical and functional evidence reclassifies a recurrent noncanonical filamin C splice-altering variant. Heart Rhythm. 2023 Aug;20(8):1158-1166. doi: 10.1016/j.hrthm.2023.05.006. Epub 2023 May 9. PubMed PMID: 37164047.PubMed ↗

2022

  • Glazer AM, Davogustto GE, Shaffer CM, Vanoye CG, Desai RR, Farber-Eger EH, Dikilitas O, Shang N, Pacheco JA, Yang T, Muhammad A, Mosley JD, Van Driest SL, Wells QS, Shaffer LL, Kalash OR, Wada Y, Bland HT, Yoneda ZT, Mitchell DW, Kroncke BM, Kullo IJ, Jarvik GP, Gordon AS, Larson EB, Manolio TA, Mirshahi T, Luo JZ, Schaid D, Namjou B, Alsaied T, Singh R, Singhal A, Liu C, Weng C, Hripcsak G, Ralston JD, McNally EM, Chung WK, Carrell DS, Leppig KA, Hakonarson H, Sleiman P, Sohn S, Glessner J, Denny J, Wei WQ, George A Jr, Shoemaker MB, Roden DM; eMERGE Network. Arrhythmia Variant Associations and Reclassifications in the eMERGE-III Sequencing Study. Circulation. 2022 Mar 22;145(12):877-891. doi: 10.1161/CIRCULATIONAHA.121.055562. Epub 2021 Dec 21. PubMed PMID: 34930020.PubMed ↗
  • Gulsevin A, Glazer AM, Shields T, Kroncke BM, Roden DM, Meiler J. Veratridine Can Bind to a Site at the Mouth of the Channel Pore at Human Cardiac Sodium Channel NaV1.5. Int J Mol Sci. 2022 Feb 17;23(4):2225. doi: 10.3390/ijms23042225. PMID: 35216338; PMCID: PMC8878851.PubMed ↗
  • Chai-Ann Ng, PhD, Rizwan Ullah, PhD, Jessica Farr, Adam P. Hill, PhD, Krystian A. Kozek, PhD, Loren R. Vanags, BSc, Devyn W. Mitchell, BSc, Brett M. Kroncke, PhD* and Jamie I. Vandenberg*, MBBS, PhD 1,2,**A Massively Parallel Assay Accurately Discriminates Between Functionally Normal and Abnormal Variants in a Hotspot Domain of KCNH2, Am J Hum Genet. 2022 Jul 7;109(7):1208-1216. doi: 10.1016/j.ajhg.2022.05.003. Epub 2022 Jun 9. PMID: 35688148. *co-corresponding authorPubMed ↗
  • Connie Jiang, Ebony Richardson, Jessica Farr, Adam P. Hill, Rizwan Ullah, Brett M. Kroncke, Steven M. Harrison, Kate L. Thomson, Jodie Ingles, Jamie I. Vandenberg, and Chai-Ann Ng, A calibrated functional patch clamp assay to enhance clinical variant interpretation in KCNH2-related long QT syndrome. Am J Hum Genet. 2022 Jul 7;109(7):1199-1207. doi: 10.1016/j.ajhg.2022.05.002. Epub 2022 Jun 9. PMID: 35688147PubMed ↗

2021

  • Kozek K, Wada Y, Sala L, Denjoy I, Egly C, O'Neill MJ, Aiba T, Shimizu W, Makita N, Ishikawa T, Crotti L, Spazzolini C, Kotta MC, Dagradi F, Castelletti S, Pedrazzini M, Gnecchi M, Leenhardt A, Salem JE, Ohno S, Zuo Y, Glazer AM, Mosley JD, Roden DM, Knollmann BC, Blume JD, Extramiana F, Schwartz PJ, Horie M, Kroncke BM*. Estimating the Posttest Probability of Long QT Syndrome Diagnosis for Rare KCNH2 Variants. Circ Genom Precis Med. 2021 Aug;14(4):e003289. doi: 10.1161/CIRCGEN.120.003289. Epub 2021 Jul 26. PMID: 34309407; PMCID: PMC8373797. *corresponding authorPubMed ↗

2020

  • AM Glazer, BM Kroncke, KA Matreyek, T Yang, Y Wada, T Shields, JE Salem, DM Fowler, DM Roden. Deep mutational scan of an SCN5A voltage sensor. Circ Genom Precis Med. 2020 Feb;13(1):e002786. doi: 10.1161/CIRCGEN.119.002786. Epub 2020 Jan 12.DOI ↗
  • Kroncke BM*, Smith DK, Zuo Y, Glazer AM, Roden DM, Blume JD. A Bayesian method to estimate variant-induced disease penetrance. PLoS Genet. 2020 Jun;16(6):e1008862. PubMed PMID: 32569262; PubMed Central PMCID: PMC7347235. *corresponding authorPubMed ↗
  • Kozek KA, Glazer AM, Ng CA, Blackwell D, Egly CL, Vanags LR, Blair M, Mitchell D, Matreyek KA, Fowler DM, Knollmann BC, Vandenberg JI, Roden DM, Kroncke BM*. High-throughput discovery of trafficking-deficient variants in the cardiac potassium channel KV11.1. Heart Rhythm. 2020 Dec;17(12):2180-2189. doi: 10.1016/j.hrthm.2020.05.041. Epub 2020 Jun 6. PubMed PMID: 32522694. *corresponding authorPubMed ↗
  • Glazer AM, Wada Y, Li B, Muhammad A, Kalash OR, O'Neill MJ, Shields T, Hall L, Short L, Blair MA, Kroncke BM, Capra JA, Roden DM. High-Throughput Reclassification of SCN5A Variants. Am J Hum Genet. 2020 Jul 2;107(1):111-123. doi: 10.1016/j.ajhg.2020.05.015. Epub 2020 Jun 12. PMID: 32533946; PMCID: PMC7332654.PubMed ↗

2019

  • JE Salem, MB Shoemaker , L Bastarache, C Shaffer, AM Glazer, BM Kroncke, Q Wells, P Straub, G Jarvik, E Larson, DV Edwards, T Edwards, L Davis, H Hakonarson, C Weng, D Fasel, BM Knollmann, T Wang, P Ellinor, J Denny, DM Roden, J Mosley, Polygenic Predictors of Thyroid Function Associate with Atrial Fibrillation, JAMA Cardiology, Volume 4, (2019)
  • BM Kroncke*, T Yang, DM Roden. Multiple mechanisms underlie increased cardiac late sodium current. Heart Rhythm. Volume 16, (2019) *corresponding author
  • BM Kroncke*, J Mendenhall, DK Smith, CR Sanders, JA Capra, AL George, Jr., JD Blume, J Meiler, and DM Roden, Protein structure aids predicting functional perturbation of missense variants in SCN5A and KCNQ1. Computational and Structural Biotechnology Journal. Volume 17, (2019) *corresponding author
  • NV Chavali, DO Kryshtal, SS Parikh, L Wang, AM Glazer, DJ Blackwell, BM Kroncke, MB Shoemaker, BC Knollmann. Patient-independent human induced pluripotent stem cell model: A new tool for rapid determination of genetic variant pathogenicity in long QT syndrome. Heart Rhythm. 2019 Nov;16(11):1686-1695. doi: 10.1016/j.hrthm.2019.04.031. PubMed PMID: 31004778.PubMed ↗
  • Daniel LL,* Yang T,* Kroncke BM*, Hall L, Stroud D, Roden DM. SCN5A variant R222Q generated abnormal changes in cardiac sodium current and action potentials in murine myocytes and Purkinje cells. Heart Rhythm. 2019 Nov;16(11):1676-1685. doi: 10.1016/j.hrthm.2019.05.017. PubMed PMID: 31125670. *co-first authorPubMed ↗

2018

  • BM Kroncke, T Yang, P Kannankeril, MB Shoemaker, DM Roden. Exploiting ion channel structure to assess rare variant pathogenicity. Heart Rhythm. Volume 15, Issue 6, 890–894 (2018)
  • CN Johnson, F Potet, MK Thompson, BM Kroncke, AM Glazer, MW Voehler, BC Knollmann, AL George, Jr., and WJ Chazin. Ca 2+ Regulation of Cardiac Sodium Channel Inactivation by Calmodulin. Structure, Volume 26, Issue 5, 683 – 694 (2018)
  • BM Kroncke, AM Glazer, DK Smith, JD Blume, DM Roden. SCN5A (NaV1.5) Variant Functional Perturbation and Clinical Presentation: Variants of a Certain Significance. Circ. Genetics. Volume 11, Issue 5 (2018)
  • DM Roden, AM Glazer, BM Kroncke. Arrhythmia genetics: Not dark and lite, but fifty shades of grey. Heart Rhythm, Volume 15, issue 8, (2018)

2017

  • CL Deatherage, Z Lu, BM Kroncke, Ma S, J Smith, M Voehler, R McFeeters, CR Sanders. Structural and Biochemical Differences between the Transmembrane Domains of Notch1 and the Amyloid Precursor Protein. Sci. Adv., e1602794 (2017)
  • B Li, JL Mendenhall, BM Kroncke, KC Taylor, H Huang, CG Vanoye, DK Smith, JD Blume, AL George, CR Sanders, J Meiler. Predicting the Functional Impact of KCNQ1 Variants of Unknown Significance. Circ. Genetics. Volume 10, Issue 5 (2017)
  • DK Smith, LE Smith, BM Kroncke, FT Billings, J Meiler, JD Blume. An Empirical Bayes Approach to Regularization Using Previously Published Models. arXiv:1710.03866v1, 11 Oct 2017.

2016

  • Kroncke BM, Van Horn WD, Smith J, Kang C, Welch RC, Song Y, Nannemann DP, Taylor KC, Sisco NJ, George AL Jr, Meiler J, Vanoye CG, Sanders CR. Structural basis for KCNE3 modulation of potassium recycling in epithelia. Sci Adv. 2016 Sep 9;2(9):e1501228. doi: 10.1126/sciadv.1501228. PubMed PMID: 27626070; PubMed Central PMCID: PMC5017827.PubMed ↗
  • Kroncke BM, Duran AM, Mendenhall JL, Meiler J, Blume JD, Sanders CR. Documentation of an Imperative To Improve Methods for Predicting Membrane Protein Stability. Biochemistry. 2016 Sep 13;55(36):5002-9. doi: 10.1021/acs.biochem.6b00537. PubMed PMID: 27564391; PubMed Central PMCID: PMC5024705.PubMed ↗

2015

  • Kroncke BM, Vanoye CG, Meiler J, George AL Jr, Sanders CR. Personalized biochemistry and biophysics. Biochemistry. 2015 Apr 28;54(16):2551-9. doi:10.1021/acs.biochem.5b00189. PubMed PMID: 25856502; PubMed Central PMCID: PMC4415889.PubMed ↗
  • Sahu ID, Craig AF, Dunagan MM, Troxel KR, Zhang R, Meiberg AG, Harmon CN, McCarrick RM, Kroncke BM, Sanders CR, Lorigan GA. Probing Structural Dynamics and Topology of the KCNE1 Membrane Protein in Lipid Bilayers via Site-Directed Spin Labeling and Electron Paramagnetic Resonance Spectroscopy. Biochemistry. 2015 Oct 20;54(41):6402-12. doi: 10.1021/acs.biochem.5b00505. PubMed PMID: 26418890; PubMed Central PMCID: PMC4812432.PubMed ↗

2014

  • Peng D, Kim JH, Kroncke BM, Law CL, Xia Y, Droege KD, Van Horn WD, Vanoye CG, Sanders CR. Purification and structural study of the voltage-sensor domain of the human KCNQ1 potassium ion channel. Biochemistry. 2014 Apr 1;53(12):2032-42. doi:10.1021/bi500102w. PubMed PMID: 24606221; PubMed Central PMCID: PMC3977583.PubMed ↗
  • Fox DA, Larsson P, Lo RH, Kroncke BM, Kasson PM, Columbus L. Structure of the Neisserial outer membrane protein Opa₆₀: loop flexibility essential to receptor recognition and bacterial engulfment. J Am Chem Soc. 2014 Jul 16;136(28):9938-46. doi: 10.1021/ja503093y. PubMed PMID: 24813921; PubMed Central PMCID: PMC4105060.PubMed ↗
  • Lo RH, Kroncke BM, Solomon TL, Columbus L. Mapping membrane protein backbone dynamics: a comparison of site-directed spin labeling with NMR 15N-relaxation measurements. Biophys J. 2014 Oct 7;107(7):1697-702. doi: 10.1016/j.bpj.2014.08.018. PubMed PMID: 25296323; PubMed Central PMCID: PMC4190660.PubMed ↗
  • Kroncke BM,* Mittendorf KF,* Meiler J, Sanders CR. The homology model of PMP22 suggests mutations resulting in peripheral neuropathy disrupt transmembrane helix packing. Biochemistry. 2014 Oct 7;53(39):6139-41. doi: 10.1021/bi500809t. PubMed PMID: 25243937; PubMed Central PMCID: PMC4188248. *co-first authorPubMed ↗
  • Sahu ID, Kroncke BM, Zhang R, Dunagan MM, Smith HJ, Craig A, McCarrick RM, Sanders CR, Lorigan GA. Structural investigation of the transmembrane domain of KCNE1 in proteoliposomes. Biochemistry. 2014 Oct 14;53(40):6392-401. doi: 10.1021/bi500943p. PubMed PMID: 25234231; PubMed Central PMCID: PMC4196734.PubMed ↗
  • ReviewL Columbus, BM Kroncke. Solution NMR Structure Determination of Polytopic α-helical Membrane Proteins: A Guide to Spin Label Paramagnetic Relaxation Enhancement Restraints. Chapter 16, Membrane proteins Engineering, Purification and Crystallization; Methods Enzymol, Volume 557 (2014)

2013

  • Schlebach JP, Peng D, Kroncke BM, Mittendorf KF, Narayan M, Carter BD, Sanders CR. Reversible folding of human peripheral myelin protein 22, a tetraspan membrane protein. Biochemistry. 2013 May 14;52(19):3229-41. doi: 10.1021/bi301635f. PubMed PMID: 23639031; PubMed Central PMCID: PMC3762913.PubMed ↗
  • Sahu ID, McCarrick RM, Troxel KR, Zhang R, Smith HJ, Dunagan MM, Swartz MS, Rajan PV, Kroncke BM, Sanders CR, Lorigan GA. DEER EPR measurements for membrane protein structures via bifunctional spin labels and lipodisq nanoparticles. Biochemistry. 2013 Sep 24;52(38):6627-32. doi: 0.1021/bi4009984. PubMed PMID:23984855; PubMed Central PMCID: PMC3826088.PubMed ↗
  • Kroncke BM, Columbus L. Backbone ¹H, ¹³C and ¹⁵N resonance assignments of the α-helical membrane protein TM0026 from Thermotoga maritima. Biomol NMR Assign. 2013 Oct;7(2):203-6. doi: 10.1007/s12104-012-9410-1. PubMed PMID: 23011877; PubMed Central PMCID: PMC3543498.PubMed ↗

2012

  • Kroncke BM, Columbus L. Identification and removal of nitroxide spin label contaminant: impact on PRE studies of α-helical membrane proteins in detergent. Protein Sci. 2012 Apr;21(4):589-95. doi: 10.1002/pro.2038. PubMed PMID: 22389096; PubMed Central PMCID: PMC3375759.PubMed ↗
  • Johnstone SR, Kroncke BM, Straub AC, Best AK, Dunn CA, Mitchell LA, Peskova Y, Nakamoto RK, Koval M, Lo CW, Lampe PD, Columbus L, Isakson BE. MAPK phosphorylation of connexin 43 promotes binding of cyclin E and smooth muscle cell proliferation. Circ Res. 2012 Jul 6;111(2):201-11. doi: 10.1161/CIRCRESAHA.112.272302. PubMed PMID: 22652908; PubMed Central PMCID: PMC3405546.PubMed ↗

2010

  • Kroncke BM, Horanyi PS, Columbus L. Structural origins of nitroxide side chain dynamics on membrane protein α-helical sites. Biochemistry. 2010 Nov 30;49(47):10045-60. doi: 10.1021/bi101148w. PubMed PMID: 20964375; PubMed Central PMCID: PMC2991438.PubMed ↗